Proteomic analysis of MALDI-TOF spectra is a core activity of the Bioinformatics Group. The group works on three-modules software of spectrometry data processing. Spectra are decomposed using Gaussian Mixture Models and Expectation-Maximization algorithm. The group conducts also research on supervised and unsupervised classification and dimension reduction methods. We are also focused on biological and medical databases. We work on techniques of integration of databases data as well as on methods of their arrangement.
The scientific issues studied in the group are also computer tomography issues: Boundary Element Method (BEM), applications of BEM, electrical impedance tomography, optical tomography, Galerkin Boundary Element Method. The team works also on application of modified boundary element method in diffusion-based optical mammography and on electrical impedance tomography used in nondestructive monitoring of dehumidification process of the damped walls.
Computer-aided detection mechanisms are the last area of scientific interest for the bioinformatics group. The research focuses mainly on developing an interactive method for detecting colorblindness and on influence of various vision disorders on the work quality of a computer user.
By definition, gamification is the use of game-thinking and game mechanics in a non-game context in order to engage users and facilitate usage of webservices. The group researches the influence of gamification on both didactic process and improving user experience while working with web applications. Implementing elements of gaming mechanics into didactic process may be an interesting method of engaging students into learning.
Members of the research group: